4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
1-N-Cbz-4-cyanopiperidine
CAS: 161609-84-3
Molecular Formula: C14H16N2O2
4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER - Names and Identifiers
| Name | 1-N-Cbz-4-cyanopiperidine |
| Synonyms | BUTTPARK 9350-50 1-CBZ-4-CYANOPIPERIDINE 1-N-Cbz-4-cyanopiperidine 1-N-CBZ-4-CYANO-PIPERIDINE 1-N-Cbz-4-cycano-piperidine 1-N-CBZ-PIPERIDINE-4-CARBONITRILE benzyl 4-cyanopiperidine-1-carboxylate BENZYL-4-CYANOPIPERIDINE-1-CARBOXYLATE 4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 1-Piperidinecarboxylic acid, 4-cyano-, phenylmethyl ester |
| CAS | 161609-84-3 |
| InChI | InChI=1/C14H16N2O2/c15-10-12-6-8-16(9-7-12)14(17)18-11-13-4-2-1-3-5-13/h1-5,12H,6-9,11H2 |
4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER - Physico-chemical Properties
| Molecular Formula | C14H16N2O2 |
| Molar Mass | 244.29 |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Boling Point | 416.5±45.0 °C(Predicted) |
| Flash Point | 205.698°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | -3.13±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.565 |
4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER - Risk and Safety
| HS Code | 29333990 |
4-CYANO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER - Introduction
1-N-Cbz-4-cyanopiperidine is an organic compound with the chemical name 1-benzyloxycarbonyl-4-cyanopiperidine. The following is a description of its nature, use, preparation and safety information:
Nature:
1-N-Cbz-4-cyanopiperidine is a solid with a white to light yellow crystalline appearance. It has a moderate to high melting point and is soluble in organic solvents such as chloroform, dimethyl sulfoxide, and ethyl acetate.
Use:
1-N-Cbz-4-cyanopiperidine is an intermediate in organic synthesis and is widely used in the synthesis of other compounds. It can be used for the synthesis of piperidine compounds, oxamide compounds, sulfonamide compounds, these compounds have important application value in the field of medicine.
Method:
1-N-Cbz-4-cyanopiperidine can be synthesized by the following steps:
1. Dissolving 4-cyanopiperidine in anhydrous dimethyl sulfoxide;
2. Add benzyl chloroformate (Cbz-Cl) and stir the reaction;
3. After the reaction is completed, the reaction solution is poured into ice water, and the product will be precipitated in the form of solid;
4. Through filtration and washing, pure 1-N-Cbz-4-cyanopiperidine is obtained.
Safety Information:
1-N-Cbz-4-cyanopiperidine needs to be safe when operating. It is irritating to the eyes, skin and respiratory tract, so wear appropriate protective gloves and eye protection during use. Avoid inhaling its dust or solution and avoid contact with skin. If you come into contact with it, rinse immediately with plenty of water and seek medical help.
Generally speaking, 1-N-Cbz-4-cyanopiperidine is an organic synthesis intermediate with a wide range of uses, and it needs to be handled carefully during operation to ensure safety.
Nature:
1-N-Cbz-4-cyanopiperidine is a solid with a white to light yellow crystalline appearance. It has a moderate to high melting point and is soluble in organic solvents such as chloroform, dimethyl sulfoxide, and ethyl acetate.
Use:
1-N-Cbz-4-cyanopiperidine is an intermediate in organic synthesis and is widely used in the synthesis of other compounds. It can be used for the synthesis of piperidine compounds, oxamide compounds, sulfonamide compounds, these compounds have important application value in the field of medicine.
Method:
1-N-Cbz-4-cyanopiperidine can be synthesized by the following steps:
1. Dissolving 4-cyanopiperidine in anhydrous dimethyl sulfoxide;
2. Add benzyl chloroformate (Cbz-Cl) and stir the reaction;
3. After the reaction is completed, the reaction solution is poured into ice water, and the product will be precipitated in the form of solid;
4. Through filtration and washing, pure 1-N-Cbz-4-cyanopiperidine is obtained.
Safety Information:
1-N-Cbz-4-cyanopiperidine needs to be safe when operating. It is irritating to the eyes, skin and respiratory tract, so wear appropriate protective gloves and eye protection during use. Avoid inhaling its dust or solution and avoid contact with skin. If you come into contact with it, rinse immediately with plenty of water and seek medical help.
Generally speaking, 1-N-Cbz-4-cyanopiperidine is an organic synthesis intermediate with a wide range of uses, and it needs to be handled carefully during operation to ensure safety.
Last Update：2024-04-09 20:49:11
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Product Name: 1-N-Cbz-4-Cyanopiperidine Visit Supplier Webpage Request for quotation
CAS: 161609-84-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 161609-84-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
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